AZD9362

SKU: orb3173835

Description

AZD9362 is a reversible, ATP-competitive inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) and the insulin receptor (insulin receptor) with oral bioavailability. It inhibits IGF-1R enzyme activity with an IC50 value of 14 nM. AZD9362 enhances the antitumor effects of AZD5363 and can be applied in cancer research, including studies on breast cancer.

Key Properties

• CAS Number: 1905412-80-7
• MW: 494.98
• Formula: C₂₄H₂₇ClN₈O₂
• SMILES: ClC=1C(C2=C3N(N=C2)C=CC=C3)=NC(NC4=C(C)N(N=C4C)C5CCN(C([C@@H](C)O)=O)CC5)=NC1
• Target: IGF-1R

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

IGF-1R