AZD-6918

SKU: orb1741077

Description

AZD6918 is a potent and selective inhibitor of Trk tyrosine kinases. It blocks BDNF/TrkB-mediated protection against etoposide and inhibits TrkB-driven cell migration and growth in neuroblastoma models, as demonstrated in both in vitro and in vivo studies. This makes it a valuable research tool for investigating Trk signaling in oncology and neurobiology.

Research Area

Signal Transduction

Key Properties

• CAS Number: 905585-60-6
• MW: 398.41
• Formula: C₂₀H₂₀F₂N₆O
• SMILES: N([C@@H](C)C1=CC=C(F)C=C1)C2=C(C#N)C=C(F)C(NC=3C=C(OC(C)C)NN3)=N2
• Target: Trk receptor,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11567474