AZD-5991 Racemate

SKU: orb2946029

Description

AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor with IC50 <3 nM in FRET assay and induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.

Research Area

Cell Biology

Key Properties

• CAS Number: 2143010-83-5
• MW: 672.26
• Formula: C₃₅H₃₄ClN₅O₃S₂
• SMILES: O=C(O)C1=C2C=3C=CC(Cl)=C(C=4C(=NN(C4C)C)CSCC5=NN(C(=C5)CSC=6C=C(OCCC2)C=7C=CC=CC7C6)C)C3N1C
• Target: c-Myc,Bcl-2 Family

Bioactivity

• Target IC50:
  MCL1:<3 nM
• In Vitro:
  AZD-5991 Racemate is a potent Mcl-1 inhibitor, showing an IC₅₀ below 3 nM in a FRET-based assay.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(Rac)-AZD-5991, AZD5991 Racemate

Compound Identifiers

PubChem CID

131634760