AZD-3409

SKU: orb1740077

Description

AZD-3409 is a potent prenyl transferase inhibitor with greater cytotoxicity than lonafarnib in various cell lines, including MEF, A549, and MCF7 cells. It preferentially inhibits protein farnesylation over geranylgeranylation and shows potential activity in models of gefitinib-resistant breast cancer, supporting its use in oncology research for studying resistance mechanisms.

Key Properties

• CAS Number: 345915-10-8
• MW: 652.84
• Formula: C₃₄H₄₁FN₄O₄S₂
• SMILES: C(N[C@H](C(OC(C)C)=O)CCSC)(=O)C1=C(CCC2=CC=C(F)C=C2)C=CC(NC[C@@H]3C[C@H](SC(=O)C=4C=CC=NC4)CN3)=C1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11377266