Azaribine

SKU: orb1702516

Description

Azaribine (Triacetyl-6-azauridine) is a broad-spectrum antiviral agent that functions as an orotate monophosphate decarboxylase (OMPD) inhibitor. It has been utilized in research models for Zika virus infection, as well as in studies investigating psoriasis and mycosis fungoides.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Key Properties

• CAS Number: 2169-64-4
• MW: 371.30
• Purity: >99.99% (May vary between batches)
• Formula: C₁₄H₁₇N₃O₉
• SMILES: O(C(C)=O)[C@H]1[C@@H](O[C@H](COC(C)=O)[C@H]1OC(C)=O)N2C(=O)NC(=O)C=N2
• Target: Influenza Virus,Virus Protease,Antiviral

Bioactivity

• In Vitro:
  In MDCK cells, Azaribine (0-2 μM; 48 hours) exhibited cytotoxicity against MDCK cells (CC50=19.66 μM).

Storage & Handling

• Storage: store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2',3',5'-Tri-O-acetyl-6-azauridine, Azaribine, Antiviral, NSC67239, NSC-67239, NSC 67239

Compound Identifiers

PubChem CID

16574