AZ044

SKU: orb1701142

Description

AZ044 is a potent and selective small molecule inhibitor targeting phosphatidylinositol 4-kinase IIIα (PI4KIIIα). This compound is a valuable research tool for investigating phosphoinositide signaling in cellular models and has been utilized in studies exploring viral replication and lipid kinase biology.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1800017-49-5
• MW: 437.55
• Purity: 99.50% (May vary between batches)
• Formula: C₂₄H₂₇N₃O₃S
• SMILES: N(C[C@@H]1CC[C@@H](C(O)=O)CC1)C=2SC=3C(N2)=CC=C(C3)C4=CC(=O)N(CC5CC5)C=C4
• Target: PI4K,PI3K
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.57 mM);DMSO:22.5 mg/mL (51.42 mM)

Bioactivity

• Target IC50:
  PI3Kδ:<4.1 (pIC50)|PI3Kα:4.0 (pIC50)|PI3Kβ:<3.7 (pIC50)|PI3Kγ:5.0 (pIC50)|PI4KIIIα:9.0 (pIC50)|PI4KIIIβ:6.6 (pIC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AZ044, AZ-044, AZ 044, PI4KIIIα

Compound Identifiers

PubChem CID

122184544