AZ-TAK1

SKU: orb1738739

Description

AZ-Tak1 is a potent, selective TAK1 kinase inhibitor (IC50 = 0.009 mM). It induces dose- and time-dependent apoptosis in mantle cell lymphoma cell lines (e.g., Mino, SP53, Jeko) by reducing p38 and ERK levels. This compound is a valuable research tool for studying TAK1 signaling in oncology and inflammation, both in vitro and in vivo.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1413440-36-4
• MW: 477.53
• Formula: C₂₅H₂₈FN₇O₂
• SMILES: FC=1C(C=2N3C(=NC2)C=CC=N3)=NC(NC4=CC(OCCN5CCC(O)CC5)=CC(CC)=C4)=NC1
• Target: Others,MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71543324