AZ-4217

SKU: orb1701136

Description

AZ-4217 is a potent BACE1 inhibitor with an IC50 of 160 pM in human SH-SY5Y cells. It demonstrates acute central efficacy in vivo, reducing amyloid plaque deposition in models like Tg2576 mice, supporting its use in Alzheimer's disease research.

Research Area

Neuroscience

Key Properties

• CAS Number: 1383846-83-0
• MW: 476.54
• Formula: C₃₀H₂₅FN₄O
• SMILES: NC1=N[C@](C=2C1=C(F)C=CC2)(C3=CN(CC)C(=O)C(C)=C3)C4=CC(=CC=C4)C=5C=C(C#CC)C=NC5
• Target: Others,Beta-Secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57406537