AY 77

SKU: orb1690071

Description

AY 77 is a potent and selective PAR2 agonist, demonstrating differential EC50 values for Ca2+ mobilization (40 nM) and ERK1/2 phosphorylation (2 µM). This compound has been shown to stimulate the migration of human breast cancer cells in vitro, making it a useful research tool for studying PAR2 signaling in oncology and inflammation.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1835734-92-3
• MW: 404.5
• Purity: 99.70% (May vary between batches)
• Formula: C₂₁H₃₂N₄O₄
• SMILES: [C@H](CC1CCCCC1)(C(N[C@H](C(N)=O)[C@@H]2CCCCC2)=O)NC(=O)C3=CC=NO3
• Target: ERK,Protease-activated Receptor,Calcium Channel
• Solubility: Ethanol:0.9 mg/mL (2.22 mM)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AY 77, AY77, AY-77, Ca(2+) receptor, CalciumChannel, Calcium Channel, ERK2, ERK1, PAR2, Proteaseactivated Receptor, ProteaseactivatedReceptor, Unk-Cha-Chg-NH2

Compound Identifiers

PubChem CID

137654325