AXL/Angiokinase-IN-1

SKU: orb2944874

Description

AXL/Angiokinase-IN-1 (compound 11b) is a potent, low-toxicity AXL/triple angiokinase inhibitor (IC50=3.75 nM for AXL). It suppresses EMT and metastasis in cancer cell models (e.g., Bxpc-3, lung cancer), impairs stromal cell functions, and induces apoptosis, demonstrating utility in oncology and metastasis research.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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MW	544.09
Formula	C₃₁H₃₄ClN₅O₂
Target	VEGFR,PDGFR,Apoptosis,FGFR

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

VEGFR,PDGFR,Apoptosis,FGFR

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