Axl-IN-19

SKU: orb3027801

Description

Axl-IN-19 (Compound 68) is a selective inhibitor of AXL, a membrane-bound receptor tyrosine kinase, with an IC50 of 5.3 nM and a cellular KD of 6.8 nM. In rats, Axl-IN-19 demonstrates favorable pharmacokinetic properties, featuring low clearance and moderate bioavailability, and is applicable for cancer research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2870696-46-9
• MW: 507.63
• Formula: C₃₁H₃₃N₅O₂
• SMILES: C(N(C)C)(=O)C1=CC=C(C=2C3=CC(C=4C=C5CC[C@@H](N6C7CC6COC7)CCC5=CC4)=CN=C3NN2)C=C1
• Target: TAM Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

TAM Receptor