AX-9657

SKU: orb3174702

Description

KRP-109 is a neutrophil elastase (NE) inhibitor known for its ability to alleviate lung inflammation. In mouse models, KRP-109 has been shown to increase survival rates and reduce both the number of neutrophils in alveolar walls and the severity of inflammation. It significantly decreases cell and neutrophil counts, along with cytokine levels (such as interleukin 1β and macrophage inflammatory protein 2) in bronchoalveolar lavage fluid. KRP-109 is applicable for investigating severe pneumonia.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 1015439-77-6
• MW: 394.48
• Formula: C₂₂H₂₆N₄O₃
• SMILES: C(C)C1=C2C(N=C(OC2=O)C3=C(N=CC=C3)N4C[C@@H](N(C)C)CC4)=CC(OC)=C1
• Target: Serine Protease

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Serine Protease