AWD12-281 sodium

SKU: orb1739865

Description

AWD 12-281 is a selective PDE4 inhibitor developed for inhalative treatment of lung inflammation. Research demonstrates its efficacy in a guinea pig model of allergic skin inflammation and its ability to suppress Th1 and Th2 cytokines in mice, highlighting its potential for treating conditions like atopic dermatitis.

Key Properties

• CAS Number: 247584-21-0
• MW: 480.25
• Formula: C₂₂H₁₃Cl₂FN₃NaO₃
• SMILES: ClC1=CN=CC(Cl)=C1NC(C(C(C2=C3)=CN(CC4=CC=C(C=C4)F)C2=CC=C3[O-])=O)=O.[Na+]
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23671009