Avatrombopag maleate

• Catalog Number: orb1740592
• Category: Small Molecules
• Description: Avatrombopag maleate
• Purity: 98.00%
• MW: 765.72
• Biological Activity: Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 may be useful in the treatment of patients with thrombocytopenia. Avatrombopag was first approved in 2018.
• CAS Number: 677007-74-8
• Formula: C₃₃H₃₈Cl₂N₆O₇S₂
• SMILES: OC(=O)\C=C/C(O)=O.OC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1nc(-c2cc(Cl)cs2)c(s1)N1CCN(CC1)C1CCCCC1
• Storage: -20°C
• Note: For research use only