Avadomide HCl

SKU: orb1701147

Description

Avadomide (CC-122) is a cereblon-binding immunomodulatory agent that degrades Ikaros and Aiolos, exhibiting direct antitumor and immunostimulatory effects. Its activity against diffuse large B-cell lymphoma (DLBCL) has been demonstrated in both in vitro and in vivo models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 1398053-45-6
• MW: 322.75
• Formula: C₁₄H₁₅ClN₄O₃
• SMILES: Cl.O=C1NC(=O)C(N2C(=O)C3=C(N=C2C)C=CC=C3N)CC1
• Target: E1/E2/E3 Enzyme,Others,NF-κB,Apoptosis,Molecular Glues

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

60199173