Aurora Kinases-IN-4

SKU: orb1944457

Description

Aurora Kinases-IN-4 (Compound 11c) is a potent, covalent ATP-competitive inhibitor of Aurora A kinase (IC50 = 1.7 nM). It exhibits anti-proliferative activity in various cancer cell lines, including triple-negative breast cancer models, making it a valuable chemical probe for oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2877011-84-0
• MW: 468.55
• Formula: C₂₆H₂₈N₈O
• SMILES: N(C=1C2=C(N=C(N1)C3=CC=C(NC(C=C)=O)C=C3)C=C(C=C2)N4CCN(C)CC4)C5=NNC(C)=C5
• Target: Aurora Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166517368