Aurora Kinases-IN-3

SKU: orb1744867

Description

Aurora Kinases-IN-3 is an orally bioavailable inhibitor of Aurora B kinase (AURKB). Its primary mechanism involves disrupting the mitotic localization of AURKB rather than directly blocking its kinase activity toward histone H3. This compound is a valuable research tool for studying mitotic progression and has demonstrated utility in both cellular and in vivo models of cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2840558-83-8
• MW: 419.35
• Formula: C₂₀H₁₆F₃N₃O₄
• SMILES: O(C1=C(C=CC=N1)C=2C=C(OC)N=CC2)C3=CC(C(NC)=O)=CC(OC(F)(F)F)=C3
• Target: Aurora Kinase,PLK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166176934