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Aurora kinase ligand-1

SKU: orb3136578

Description

Aurora kinaseligand-1 (Compound I-4) is an AURKB PROTAC ligand designed to target aurora kinase B. It can conjugate with an E3 ligase ligand and a linker to form the AURKB PROTAC degrader MS44, which is applicable in cancer research.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1907679-70-2
MW479.51
FormulaC24H26FN7O3
SMILESO=C(NC=1C=CC=C(F)C1)CC2=NNC(=C2)NC=3N=CN=C4C=C(OCCCNCCO)C=CC43
TargetLigands for Target Protein for PROTAC,Aurora Kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information