Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Aurora-A ligand 1

SKU: orb2945945

Description

Aurora-A ligand 1 is a potent, selective Aurora-A inhibitor (Kd = 0.85 nM) used as a target-binding moiety in PROTAC degraders. It serves as a key intermediate in synthesizing compounds like HLB-0532259, which demonstrate antitumor activity in neuroblastoma models in vitro and in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2541626-73-5
MW393.439
FormulaC21H23N5O3
SMILESO=C(O)C1=CC=C(C=C1)NC=2N=CC=3C=C(C(=O)N(C)C)N(C3N2)C4CCCC4
TargetLigands for Target Protein for PROTAC,Aurora Kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • ENMD-2076 [orb1223607]

    >98% (HPLC)

    934353-76-1

    375.4701

    C21H25N7

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information