Aurkin A

SKU: orb2646346

Description

Aurkin A is a small molecule conformational inhibitor that selectively targets the TPX2-binding site of Aurora A kinase (Aurka) with a Kd of 3.77 µM. It is a valuable research tool for studying mitotic spindle assembly and has been utilized in both in vitro biochemical assays and cellular studies to probe Aurora A function in cancer models.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 1534060-58-6
• MW: 346.15
• Formula: C₁₆H₉BrFNO₂
• SMILES: O=C(O)C=1C=C(N=C2C(F)=CC=CC21)C=3C=CC=C(Br)C3
• Target: Aurora Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

80043125