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AURKA-IN-3

SKU: orb3173175

Description

AURKA-IN-3 (Compound AL8) is an irreversible covalent inhibitor of Aurora kinase A (AURKA) with an IC50 of 23.0 nM. It inhibits the activation of AURKA-mediated cAMP and phospholipase C (PLC) signaling pathways, as well as reduces the autophosphorylation of AURKA. AURKA-IN-3 is a potential candidate for research into malignancies associated with high AURKA expression, such as leukemia and lymphoma.

Research Area

Cell Biology, Epigenetics & Chromatin

Images & Validation

Key Properties

TargetAurora Kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information