Auristatin23

SKU: orb1685605

Description

Auristatin 23 is a potent small molecule antitumor agent that inhibits the proliferation of various cancer cell lines in vitro. Its mechanism and efficacy are subjects of ongoing research in oncology and drug discovery, including investigations into its potential for antibody-drug conjugate (ADC) payload applications.

Key Properties

• CAS Number: 2375388-36-4
• MW: 917.23
• Purity: 99.74% (May vary between batches)
• Formula: C₄₉H₈₄N₆O₁₀
• SMILES: [C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(CCCCN(C(OC(C)(C)C)=O)C)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
• Target: Others
• Solubility: DMSO:9.18 mg/mL (10.01 mM)

Bioactivity

• In Vitro:
  Auristatin23 exhibits IC50 of 0.4-6.2nM for melanoma and colon cancer cell lines.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Auristatin23

Compound Identifiers

PubChem CID

118914551