AUNP-12 acetate

SKU: orb1296762

Description

AUNP-12 acetate is a synthetic peptide inhibitor of the PD-1 immune checkpoint. It demonstrates potent activity in suppressing lymphocyte proliferation and function in vitro, while promoting immune activation and antitumor efficacy in preclinical cancer research models.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• Target: PD-1/PD-L1
• MW: 3321.61
• Purity: 99.29% (May vary between batches)
• Formula: C₁₄₄H₂₃₀N₄₀O₅₀
• SMILES: O=C([C@@](NC([C@](NC([C@@](NC([C@@](NC([C@@](NC([C@@](NN)(CCC(O)=O)[H])=O)(CCCCN)[H])=O)([C@@](CC)(C)[H])[H])=O)(CCC(N)=O)[H])=O)(C)[H])=O)(CCCCN)[H])N1[C@@](CCC1)(C(N[C@@](C(C([C@@](NC([C@@](NC([C@@](NC([C@@](NC([C@@](NC([C@@](NC(C(CCCCNN[C@@](CC2=CC=CC=C2)(C(N([H])[C@](C(N[C@@](C(CC(O)=O)([H])[H])(C(N[C@](C(N[C@@]([C@@](O)(C)[H])(C(N[C@@](CC(N)=O)(C(N[C@@](CO)(C([H])=O)[H])=O)[H])=O)[H])=O)(CO)[H])=O)[H])=O)(CO)[H])=O)[H])NC([C@@](N([H])C([C@@](NC([C@@](NC([C@@](NC([C@@](NC([C@@](NC([C@@](N)(CO)[H])=O)(CC(N)=O)[H])=O)([C@@](O)(C)[H])[H])=O)(CO)[H])=O)(CCC(O)=O)[H])=O)(CO)[H])=O)(CC3=CC=CC=C3)[H])=O)=O)(CC4=CC=CC=C4)[H])=O)(CCCNC(N)=N)[H])=O)(C(C)(C)[H])[H])=O)([C@@](O)(C)[H])[H])=O)(CCC(N)=O)[H])=O)(CC(C)C)[H])=O)=O)(C)[H])=O)[H].CC(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PD-L1, PDL1, PD1/PDL1, PD1, PD-1, 1353563-85-5, 1353563-85-5 Free base, AUNP 12 acetate, AUNP 12 Acetate, AUNP12 acetate, AUNP12 Acetate, AUNP-12 Acetate, AUNP-12 acetate (1353563-85-5 Free base)

Compound Identifiers

PubChem CID

168013582