ATX-IN-1

SKU: orb2944381

Description

ATX-IN-1 (compound 35) is a potent, orally bioavailable ATX inhibitor (IC50 = 0.7 nM) with anti-inflammatory and anti-fibrotic properties. It suppresses the TGF-β/Smad pathway and collagen deposition, demonstrating efficacy in a bleomycin-induced pulmonary fibrosis mouse model, making it a valuable tool for fibrosis and inflammation research.

Research Area

Metabolism Research

Key Properties

• MW: 486.48
• Formula: C₂₅H₂₂N₆O₅
• Target: PDE

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PDE