Atuveciclib S-Enantiomer

SKU: orb1710321

Description

Atuveciclib S-Enantiomer (BAY-1143572 S-Enantiomer) is the selective (S)-enantiomeric form of a potent CDK9 inhibitor, exhibiting an IC50 of 16 nM against the CDK9/CycT1 complex. Its application in research includes investigating transcription regulation in oncology, with studies demonstrating antitumor activity in both cellular and animal models of hematological cancers.

Research Area

Cell Biology

Key Properties

• CAS Number: 2250279-81-1
• MW: 387.43
• Formula: C₁₈H₁₈FN₅O₂S
• SMILES: O(C)C1=C(C=CC(F)=C1)C=2N=C(NC3=CC(CS(C)(=N)=O)=CC=C3)N=CN2
• Target: CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71618220