ATR-IN-9

SKU: orb1690849

Description

ATR-IN-9 is a potent and selective ATR kinase inhibitor with an IC50 of 10 nM. It is a valuable chemical probe for studying DNA damage response pathways in cancer research, demonstrating utility in both in vitro cellular assays and in vivo xenograft models to investigate chemosensitization and synthetic lethality.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2417513-43-8
• MW: 421.505
• Formula: C₂₂H₂₇N₇O₂
• SMILES: C[C@@H]1COCCN1c1cc(c2cnn(-c3cc[nH]n3)c2n1)C1(O)CCC(C)(CC1)C#N
• Target: ATM/ATR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155585610