ATR-IN-32

SKU: orb3173647

Description

ATR-IN-32 is an orally active ATR inhibitor that effectively suppresses the proliferation of MIA PaCa-2 cells. It significantly inhibits tumor growth in mice bearing LOVO and HT-29 xenografts. ATR-IN-32 is applicable for studying cancers mediated by the ATR protein kinase, such as colorectal cancer and pancreatic cancer.

Research Area

Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2902715-97-1
• MW: 404.47
• Formula: C₂₂H₂₄N₆O₂
• SMILES: C(#N)C1(C=2C3=C(C(=NC=C3)C=4C=CNN4)N=C(C2)N5[C@H](C)COCC5)CCOCC1
• Target: ATM/ATR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ATM/ATR