ATR-IN-23

SKU: orb1944403

Description

ATR-IN-23 (Compound 34) is a highly potent and selective ATR inhibitor with an IC50 of 1.5 nM. It demonstrates antiproliferative activity in LoVo cells and synthetic lethality in HT-29 cells, supporting its use as a research tool for investigating DNA damage response pathways and associated cancer models in vitro.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2923800-62-6
• MW: 458.56
• Formula: C₂₀H₂₂N₆O₃S₂
• SMILES: N(C)C=1N(C2=NC(=C3C(=N2)C(S(C)(=O)=O)=CS3)N4[C@H](C)COCC4)C=5C(N1)=CC=CC5
• Target: ATM/ATR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168355512