ATR-IN-18

SKU: orb1686436

Description

ATR-IN-18 is a potent and orally bioavailable ATR kinase inhibitor with an IC50 of 0.69 nM. It demonstrates anti-proliferative activity in LoVo colorectal cancer cells (IC50: 37.34 nM) and has shown promising anti-tumor efficacy in research models, supporting its investigation in oncology and DNA damage response studies.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2766407-55-8
• MW: 517.48
• Formula: C₁₉H₂₂F₃N₇O₅S
• SMILES: OC(=O)C(F)(F)F.C[C@@H]1COCCN1c1nc2n(ncc2c2N(CCc12)S(C)(=O)=O)-c1cc[nH]n1
• Target: ATM/ATR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163408903