ATR-IN-15

SKU: orb1688449

Description

ATR-IN-15 (compound 1) is a potent, orally bioavailable ATR kinase inhibitor (IC50 = 8 nM) with additional activity against DNA-PK and PI3K. It demonstrates efficacy in cellular models, such as LoVo colon tumor cells, making it a valuable chemical probe for studying DNA damage response pathways in cancer research.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2756665-52-6
• MW: 378.43
• Formula: C₁₉H₂₂N₈O
• SMILES: CC=1N2C(=C(N1)C=3C=CNN3)N=C(C=C2N4[C@H](C)COCC4)C=5N(C)N=CC5
• Target: PI3K,ATM/ATR,Others,DNA-PK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162427557