ATR-258

SKU: orb3135061

Description

ATR-258 is a GRK2-biased partial agonist of β2AR. It acts as a competitive antagonist of β1AR and exhibits weak partial agonist activity on β3AR at a concentration of 10 μM. ATR-258 enhances glycemic control and reduces lipid accumulation in obese mice with minimal side effects. It is applicable in research on type 2 diabetes (T2DM).

Research Area

Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2301983-88-8
• MW: 212.26
• Formula: C₁₁H₁₇FN₂O
• SMILES: [C@@H](CNC(C)(C)C)(O)C=1C=C(F)C=NC1
• Target: Adrenergic Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Adrenergic Receptor