Atorvastatin Sodium

SKU: orb1705356

Description

Atorvastatin Sodium is a competitive HMG-CoA reductase inhibitor that upregulates hepatic LDL receptor expression. It also exhibits neuroprotective properties by inhibiting aquaporin 4 to mitigate cerebral edema in ischemic models. This small molecule is widely used in cardiovascular and neuroscience research, both in vitro and in vivo, to study cholesterol metabolism and neuroinflammation.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 134523-01-6
• MW: 580.63
• Purity: 99.89%
• Formula: C₃₃H₃₄FN₂NaO₅
• SMILES: O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.[Na+]
• Target: HMG-CoA Reductase,Aquaporin,LDL,Autophagy
• Solubility: DMSO:240 mg/mL (413.34 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Atorvastatin Sodium, Aquaporin, HMGCoA Reductase, HMG-CoA Reductase (HMGCR), HMGCoAReductase, LDL, Lipitor

Compound Identifiers

PubChem CID

23665101