ATM potentiator-1

SKU: orb3210851

Description

ATMpotentiator-1 (compound 9) acts as a β-lactamase inhibitor and efflux pump inhibitor with an IC50 of 1.6 μM for NDM-1, 12.5 μM and 5.4 μM for OXA-10, 5.0 μM for VIM-2, 26.7 μM for KPC-2, and 3.4 μM for OXA-48. It inhibits efflux pump activity in *Pseudomonas aeruginosa* and shows synergistic inhibitory effects when used with CCCP. ATMpotentiator-1 is applicable in research on carbapenem-resistant *Pseudomonas aeruginosa* (CRPA) infections.

Key Properties

• Target: Antibacterial

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Antibacterial