ATM-IN-13

SKU: orb3210956

Description

ATM-IN-13 (A36) is an orally active selective ATM kinase inhibitor with a human IC50 of 0.3 nM. It disrupts the ATM-mediated DNA double-strand break repair signaling pathway, reduces phosphorylation levels of ATM and p53, and inhibits the ATM-dependent DNA damage response. ATM-IN-13 is applicable in colorectal cancer research.

Key Properties

• CAS Number: 3104731-13-4
• MW: 443.58
• Formula: C₂₇H₃₃N₅O
• SMILES: N1=CC(=CC=C1OCCCN2CCCCC2)C3=CC=C4N=CC=5C(=NN(C5C4=C3)C(C)C)C
• Target: ATM/ATR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ATM/ATR