Atiprimod (free base)

SKU: orb1738304

Description

Atiprimod is an orally active azaspirane that inhibits STAT3 phosphorylation, disrupting IL-6 and VEGF signaling. This action downregulates anti-apoptotic proteins like Bcl-2, leading to cell cycle arrest and apoptosis in various cancer models, as demonstrated in both in vitro and in vivo studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 123018-47-3
• MW: 336.6
• Formula: C₂₂H₄₄N₂
• SMILES: C(CCN(CC)CC)N1CC2(CCC(CCC)(CCC)CC2)CC1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129869