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AT-56

SKU: orb1307297

Description

AT56 is a selective inhibitor of prostaglandin D2 synthase (PTGDS). It has been shown to attenuate the adipogenic effects of aldosterone in research settings. This small molecule is a useful tool for studying lipid metabolism, adipogenesis, and mineralocorticoid-related pathways in both cellular and animal models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number162640-98-4
MW397.52
Purity98.16% (May vary between batches)
FormulaC25H27N5
SMILESC(CCc1nn[nH]n1)CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12
TargetPGE Synthase
SolubilityDMSO:25 mg/mL (62.89 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM)

Bioactivity

Target IC50
L-PGDS:95 μM (IC50)|L-PGDS:Ki: 75 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Lipocalin-type, Inhibitor, inhibit, inflammatory, L-PGDS, drowsiness, AT 56, AT56, AT-56, PGE synthase, PGE Synthase, PGESynthase, synthase, prostaglandin, Prostaglandin E synthase

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 130.00
10 mg
$ 170.00
25 mg
$ 300.00
50 mg
$ 460.00
100 mg
$ 710.00
DispatchUsually dispatched within 5-10 working days
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