AST5902 mesylate(2412155-74-7 free base)

SKU: orb1298504

Description

AST5902 mesylate is the primary in vivo metabolite of the tyrosine kinase inhibitor Alflutinib and exhibits antineoplastic activity. It is utilized in oncology research to study EGFR mutation-targeted therapies, with applications in both in vitro cellular assays and in vivo pharmacokinetic and efficacy models.

Research Area

Cardiovascular Research, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2412155-75-8
• MW: 650.67
• Purity: 99.46% (May vary between batches)
• Formula: C₂₈H₃₃F₃N₈O₅S
• SMILES: OS(=O)(C)=O.C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(C)CCNC)=O
• Target: Drug Metabolite,EGFR
• Solubility: DMSO:55 mg/mL (84.53 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Drug Metabolite, DrugMetabolite, AST5902 mesylate(2412155 74 7 free base), AST5902 mesylate(2412155747 free base), AST-5902 mesylate(2412155-74-7 free base), AST5902 mesylate(2412155-74-7 free base)

Compound Identifiers

PubChem CID

146405897