AST 487

SKU: orb1303230

Description

AST 487

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 630124-46-8
• MW: 529.56
• Purity: 98.17%
• Formula: C₂₆H₃₀F₃N₇O₂
• SMILES: C(C1=C(C(F)(F)F)C=C(NC(NC2=CC=C(OC=3C=C(NC)N=CN3)C=C2)=O)C=C1)N4CCN(CC)CC4
• Target: Bcr-Abl,FLT,VEGFR,c-RET,c-Kit
• Solubility: DMSO:50 mg/mL (94.42 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.78 mM)

Bioactivity

• Target IC50:
  RET:880 nM|FLT3:520 nM.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RET, SCFR, VEGFR, Vascular endothelial growth factor receptor, NVP-AST 487, NVP-AST487, NVP-AST-487, KDR, inhibit, FLT4, Inhibitor, Fms like tyrosine kinase 3, FLT3, BcrAbl, Bcr-Abl, AST 487, AST487, AST-487, CD117, CD135, Cluster of differentiation antigen 135, c-Kit, cKit, cRET

Compound Identifiers

PubChem CID

11409972