Asperuloside

SKU: orb1222703

Description

Asperuloside has anti-inflammatory activity.

Key Properties

• CAS Number: 14259-45-1
• MW: 414.36
• Purity: >98% (HPLC)
• Formula: C₁₈H₂₂O₁₁
• SMILES: C(=O)(C)OCC1=C[C@@H]2OC(=O)C3=CO[C@H]([C@H]1[C@H]23)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO
• Target: Others
• Solubility: In Vitro: DMSO : 100 mg/mL (241.34 mM)

Bioactivity

• In Vivo:
  Animal model: Rats consuming a high fat diet (HFD). Dosage: 3 mg/day. Administration: p.o. , 0.3% in diet, daily, 12 weeks. Result: Reduced body weight, energy intake, adiposity, blood glucose, and plasma insulin.
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• In Vitro:
  Western blot analysis. Cell line: U937 cells. Concentration: 0-5 mM. Incubation time: 24 h. Result: Increased the cleaved Caspase-3, Caspase-9, and PARP, and Cyto-c release from mitochondria. Induced expression of GRP78, p-PERK, p-eIF2α, CHOP, p-IRE1, XBP1, ATF6 and cleaved Caspase-12
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others