Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

ASP2453

SKU: orb1303490

Description

ASP2453

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2241719-73-1
MW747.85
Purity99.71% (May vary between batches)
FormulaC40H48F3N7O4
SMILESCOCCCN1CCC(CC1)Oc1nc(N2CCC3(CN(C3)C(=O)C=C)CC2)c2cc(C3CC3)c(c(OCC(F)(F)F)c2n1)-c1c(C)ccc2[nH]ncc12
TargetKras,Ras,ERK
SolubilityDMSO:250 mg/mL (334.29 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.69 mM)

Bioactivity

Target IC50
KRas (G12C):40 nM (IC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

KRAS G12C, Inhibitor, inhibit, ASP 2453, ASP2453, ASP-2453, Ras
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 160.00
5 mg
$ 340.00
10 mg
$ 490.00
1 ml x 10 mM (in DMSO)
$ 500.00
25 mg
$ 740.00
50 mg
$ 980.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry