Asatone

SKU: orb1309977

Description

Asatone, a bioactive compound from Radix et Rhizoma Asari, exhibits anti-inflammatory properties by activating NF-κB while inhibiting the phosphorylation of MAPK pathways (ERK, JNK, p38). This small molecule is a useful research tool for studying inflammation mechanisms in both cellular and animal models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 38451-63-7
• MW: 448.51
• Purity: 99.92% (May vary between batches)
• Formula: C₂₄H₃₂O₈
• SMILES: [H][C@]12C(CC=C)=C[C@](OC)(C(=O)C1(OC)OC)[C@@]1(CC=C)C=C(OC)C(=O)C(OC)(OC)[C@@]21[H]
• Target: NF-κB
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.46 mM);DMSO:60 mg/mL (133.78 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, NFkB, NF-kB, NFκB, NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, Inhibitor, Asatone

Compound Identifiers

PubChem CID

10983193