AS-99 TFA

SKU: orb1693273

Description

AS-99 TFA is a potent and selective ASH1L histone methyltransferase inhibitor with anti-leukemic activity. It demonstrates efficacy in cellular assays by blocking proliferation and inducing apoptosis, and reduces leukemia burden in vivo through downregulation of MLL fusion target genes.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation

Key Properties

• CAS Number: 3115178-55-4
• MW: 707.71
• Formula: C₂₉H₃₁F₆N₅O₅S₂
• SMILES: O=C(O)C(F)(F)F.O=C(NCC=1C=CC=2C(=CN(C2C1)C3CCN(CC3)S(=O)(=O)C(F)(F)F)C=4C=CC=C(C4)C(=S)N)C5CN(C)C5
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Histone Methyltransferase