AS-85

SKU: orb1691001

Description

AS-85 is a cell-permeable small molecule inhibitor of ASH1L with demonstrated anti-leukemic activity. It suppresses the proliferation of leukemic cells in vitro and has shown efficacy in preclinical in vivo models, making it a useful chemical probe for leukemia research.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2323623-80-7
• MW: 579.66
• Purity: 98.96% (May vary between batches)
• Formula: C₂₆H₂₈F₃N₅O₃S₂
• SMILES: O=C(NCC=1C=CC=2C(=CN(C2C1)C3CCN(CC3)S(=O)(=O)C(F)(F)F)C=4C=CC=C(C4)C(=S)N)C5CNC5
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138608677