Arvanil

SKU: orb1704676

Description

Arvanil

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 128007-31-8
• MW: 439.63
• Purity: 99.49%
• Formula: C₂₈H₄₁NO₃
• SMILES: C(NC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)C1=CC(OC)=C(O)C=C1
• Target: TRP/TRPV Channel,Cannabinoid Receptor
• Solubility: Ethanol:8 mg/mL (18.2 mM)

Bioactivity

• In Vivo:
  Arvanil (2 mg/kg, intrabitoneally injected) induced anti-hyperkinetic state in rats injected with 3-nitropropionic acid (3-NP) in bilateral striatum.
• In Vitro:
  Arvanil directly binds to two amino acid sites of mitochondrial calcium uptake protein 1 (MICU1), Ser47 and Phe128, triggering iron death in living cells. Arvanil inhibits lymphocyte proliferation and IFN-γ production. Phenotypes of activated CD4+T cells treated with Arvanil showed downregulation of T cell activation markers such as CD25, HLA-DR, and CD134/OX40.

Storage & Handling

• Storage: store at low temperature,High Volatility | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N-Vanillylarachidonamide, Arvanil

Compound Identifiers

PubChem CID

6449767