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ARUK3001185

SKU: orb1689488

Description

ARUK3001185 (Compound 8l) is a potent and selective Notum inhibitor (IC50 = 6.7 nM) with oral activity and brain penetration. It is suitable for in vivo oral dosing in rodent disease models, facilitating research on Wnt signaling pathways in neurodegenerative and cognitive disorders.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2411969-39-4
MW282.05
FormulaC9H4Cl2F3N3
SMILESC(F)(F)(F)C1=C(Cl)C(=CC=C1Cl)N2C=CN=N2
TargetWnt/beta-catenin,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

ARUK3001185 (orb1689488)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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