Artobiloxanthone

SKU: orb3141624

Description

Artobiloxanthone (Compound AA3) exhibits antitumor activity, particularly against oral squamous cell carcinoma (OSCC). It inhibits the Akt/mTOR and STAT3 pathways, thereby suppressing the proliferation of SAS and T.Tn cells with IC50 values of 11 and 22 μM, respectively, as well as cancer cell migration. Artobiloxanthone induces cell apoptosis in OSCC by activating caspase3/9 and causes cell cycle arrest at the S phase.

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Key Properties

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Formula	C₂₅H₂₂O₇
Target	MMP,COX,Bcl-2 Family,STAT,Apoptosis,Caspase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

MMP,COX,Bcl-2 Family,STAT,Apoptosis,Caspase

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