Artepillin C

SKU: orb2653807

Description

Artepillin C shows antioxidant, anti-angiogenesis, and anti-tumor activities; it also shows anti-inflammatory effects mediated, at least in part, by prostaglandin E2 and nitric oxide inhibition through NF-κB modulation. Artepillin C activates the immune system, and possesses direct antitumor activity. Artepillin C can suppress alloreactive CD4 T cell responses in vitro, so it could be used as a potential immunosuppressant, either solely or as adjunct agent in treating graft versus host disease. Artepillin C promotes adipocyte differentiation and glucose uptake in part by direct binding to PPARγ, which could be the basis of the pharmacological benefits of green propolis intake in reducing the risk of type 2 diabetes.

Key Properties

• CAS Number: 72944-19-5
• MW: 300.4
• Purity: >98% (HPLC)
• Formula: C₁₉H₂₄O₃
• Target: NF-κB | IFN-γ | Foxp3 | TNF-α | IL Recepter | Antifection | PAK | AKT
• Solubility: DMSO, Pyridine, Methanol, Ethanol, etc.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB | IFN-γ | Foxp3 | TNF-α | IL Recepter | Antifection | PAK | AKT