ARTD10/PARP10-IN-1

SKU: orb1744832

Description

ARTD10/PARP10-IN-1 is a potent inhibitor targeting multiple ADP-ribosyltransferases, including ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10, and ARTD1/PARP1. Its anticancer potential has been investigated in preclinical studies for prostate and breast cancer research, utilizing both in vitro cellular assays and in vivo tumor models.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 1708103-76-7
• MW: 248.23
• Purity: 99.14% (May vary between batches)
• Formula: C₁₂H₁₂N₂O₄
• SMILES: N(C(/C=C\C(OC)=O)=O)C1=CC(C(N)=O)=CC=C1
• Target: PARP

Bioactivity

• Target IC50:
  ARTD1/PARP1:4.4 μM|PARP15:1.7 μM|ARTD10/PARP10:0.8 μM|PARP14:1.6 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PARP

Compound Identifiers

PubChem CID

118732826