ARQ-736

SKU: orb1738296

Description

ARQ 736 is a selective small-molecule BRAF inhibitor that potently targets cancer cells with BRAF mutations, which are prevalent in melanoma and linked to anti-EGFR therapy resistance in colon cancer. It is a valuable research tool for investigating the oncogenic MAPK pathway in both in vitro cellular assays and in vivo xenograft models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1228237-57-7
• MW: 674.54
• Formula: C₂₅H₂₅N₈Na₂O₈PS
• SMILES: [Na+].[Na+].Cn1ccc(n1)S(=O)(=O)N1CCC[C@H](C1)Nc1nccc(n1)-c1c(nc2occn12)-c1cccc(OCOP([O-])([O-])=O)c1
• Target: Others,Raf

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46869123