Arnicolide D

SKU: orb1297461

Description

Arnicolide D

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 34532-68-8
• MW: 332.39
• Purity: 96.66%
• Formula: C₁₉H₂₄O₅
• SMILES: [H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](OC(=O)C(C)=C)[C@]1([H])[C@H](C)C(=O)O2
• Target: Caspase,Akt,mTOR,ROS,PI3K,STAT,NF-κB,Apoptosis
• Solubility: DMSO:4.16 mg/mL (12.52 mM)

Bioactivity

• In Vitro:
  In this study, we found that two sesquiterpene lactones, isobutyroylplenolin and Arnicolide D, from Centipeda minima L. (Compositae) exerted stronger cytotoxic activity than cisplatin on the human colon carcinoma HT-29 cell line. Furthermore, the cytotoxicity of these two compounds on normal cells was weaker than that of cisplatin.

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Caspase, Arnicolide D, Akt, Mammalian target of Rapamycin, mTOR, inhibit, Inhibitor, STAT, STAT3, Protein kinase B, PKB, PI3K, Phosphoinositide 3-kinase

Compound Identifiers

PubChem CID

182199